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Integrated stress response : ウィキペディア英語版 | Integrated stress response Integrated Stress Response (ISR) is a cellular stress response common to all eukaryotes. ISR is a common denominator of different types of cellular stresses resulting in activation of at least one of the eIF-2 alpha (EIF2S1). ISR results in the: *Down regulation of the general protein synthesis (CAP-dependent) *Up regulation of translation and expression of certain transcription factors, e.g. Activating Transcription Factor 4 (ATF4) ==References==
抄文引用元・出典: フリー百科事典『 ウィキペディア(Wikipedia)』 ■ウィキペディアで「Integrated stress response」の詳細全文を読む
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